PEDIATRIC DIABETES RESEARCH CENTER

Jane J. Kim, MD

Assistant Professor, UCSD Department of Pediatrics
phone: 858-534-8228
e-mail: janekim@ucsd.edu
Funding

Biography

Dr. Jane Kim is an assistant professor at UCSD’s Department of Pediatrics and a physician-scientist in the UCSD Division of Pediatric Endocrinology. Her medical education began at the University of Toronto, followed by a pediatric residency at the Hospital for Sick Children.

Committed to pursuing endocrine research that integrates molecular biology, genetics and medicine, Dr. Kim moved to the National Institutes of Health (NIH) Headquarters. There, Dr. Kim complete her pediatric endocrinology fellowship. Going to specialize in diabetes research, Dr. Kim did her postdoctoral research training at the Naomi Berrie Diabetes Center at Columbia University, New York. In 2004, Dr. Kim joined the UCSD faculty at the School of Medicine.

Research Interests

Specifically, her research investigates how insulin acts at the cellular level in different tissues to alter glucose metabolism and other physiologic events in diabetes. Discovering mechanisms that govern targets of insulin signaling is expected to lead to novel treatments in treating diabetes.

Recent Publications

Kim JJ, Li P, Huntley J, Chang JP, Arden KC, Olefsky JM. FoxO1 haploinsufficiency protects against high fat diet-induced insulin resistance with enhanced PPARgamma activation in adipose tissue. Diabetes 58:1275-82

Kim JJ, Park BC, Kido Y, Accili 2009 Fan WQ, Imamura T, Sonoda N, Sears D, Patsouris D, Kim JJ, Olefsky JM. FOXO1 transrepresses PPARgamma transactivation, coordinating an insulin-induced feed-forward response in adipocytes. J Biol Chem 284:12188-97

Kim JJ, Kido Y, White MF, Scherer PE, Accili D. Analysis of compensatory β cell failure in mice with combined mutations of Insulin Receptor and Irs2. Am J Physiol Endo 292:E1694-701.

D. Mitogenic and metabolic effects of type I IGF receptor overexpression in insulin receptor-deficient hepatocytes. Endocrinology 142:3354-60.