Dr. Jianhua Shao was recently recruited to UCSD as an associate professor in the Department of Pediatrics. His medical education began overseas at Xinxiang Medical College, China, where he received his MD degree and practiced as an endocrinologist.
In 1992, Dr. Shao began his basic research career, earning his PhD degree from the Beijing Medical University. During his postdoctoral training at Case Western Reserve University and University of Colorado Health Sciences Center, he studied the insulin signaling abnormalities in human and mouse models of gestational diabetes.
Dr. Shao was appointed as a faculty member of the Graduate Center for Nutritional Sciences at the University of Kentucky in 2004 and established his independent laboratory where his research was focused on obesity and type 2 diabetes.
Dr. Shao’s main research is focused on understanding and demonstrating the underlying process of insulin resistance during the development of obesity.
Qiao, L., Zou, C.H., van der Westhuyzen, D.R., and J. Shao. Adiponectin Reduces Plasma Triglyceride by Increasing VLDL-Triglyceride Catabolism. Diabetes. 2008, 57:1824-1833
Qiao, L., Zou, C.H., Jerome Schaack, Peter F. Johnson and J. Shao. Transcriptional Regulation of Fatty Acid Translocase/CD36 Expression by CCAAT/Enhancer-Binding Protein α. Journal of Biological Chemistry. 2008, 283(14): 8788-8795
J.M. Schroeder-Gloeckler, S.M. Rahman, R.C. Janssen, L. Qiao, J. Shao, M. Roper, et al., CCAAT/enhancer-binding protein beta (C/EBPbeta ) deletion reduces adiposity, hepatic steatosis, and diabetes in Leprdb/db mice. Journal of Biological Chemistry. 2007, 282: 15717 – 15729
Qiao, L., Schaack, J., and J. Shao. Suppression of Adiponectin Gene Expression by Histone Deacetylase Inhibitor Valproic Acid. Endocrinology. 2006, 147(2): 865-874.